The Unblinding: Has Lilly Solved The Alzheimer’s Puzzle?

Eli Lilly and Company has spent three decades and $3 billion in an Ahab-like quest to develop the world’s first effective drug to treat Alzheimer’s disease.
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Perfect Chemistry: Ambre Blends Fragrance’s Formula for Success

How Ambre Blends fragrances won a cult-like hold on our noses—and boomed into a big-money business

Strange Brew: The Story of Three Floyds' Success

Editor's Note: This story is a companion piece from our archives to the April 2012 Local Beer issue of the magazine.
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Speed Read on Indy’s Coworking Culture

Gone are the days of staking out a spot, Land Rush–style, in a cramped coffee shop and taking conference calls in the bathroom. Here, a guide to navigating Indy’s hottest new coworking spaces.
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The Future Of Downtown

It’s no secret that downtown has a skyline-sized problem brought on by the pandemic. But a historic slate of development is underway that may revitalize the city’s core to its Super Bowl–era glory. Here, a tour of what’s working, what’s not, and what remains to be seen.

Can All-Star Paul George Become a Bona Fide Celebrity?

Paul George is a soft-spoken homebody who’s pictured more often with a fishing pole in his hand than a martini glass. The good news: George says he likes the newfound attention. “Now it’s just [about] getting out of my comfort zone and being part of big events,” he says.
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Our Top 10 Stories of 2013

Including one of Indiana's biggest cons, a complicated woman in her final days, a reality-TV hilljack, the crafty governor-elect, a big-deal farmer, the coupling of an actress and a corn-fed rocker, and more.
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Jared Fogle Inc.: The Business of Being Subway's Star

“The joke is, my dad always asks me, ‘When are you going to get a real job?’” Fogle says. “I’m like, ‘Hopefully not for a while.’ I love what I do.”
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Emmis Communications Endorses Freedom Indiana's Fight Against HJR-6

“Indiana has traditionally had a friendly business environment that is the backbone of the Hoosier economy,” says CEO Jeff Smulyan. “This is two steps backward and runs counter to what businesses are demanding."

Six Bates-Hendricks Businesses That Deserve A Visit

Whether you want to shop, go for a stroll, or get a cup of coffee, East Street has something for you.